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Showing results for accolate. Your search for laccolite retrieved no results.

Select item 93286501.

Zafirlukast is a broad‐spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times

Lisa‐Marie Holbrook, Shirley J. Keeton, Parvathy Sasikumar, Sophie Nock, Justine Gelzinis, Elizabeth Brunt, Sarah Ryan, Megan M. Pantos, Christina A. Verbetsky, Jonathan M. Gibbins, Daniel R. Kennedy

Br J Pharmacol. 2021 Feb; 178(3): 550–563. Published online 2021 Jan 4. doi: 10.1111/bph.15291

PMCID:: PMC9328650

Article PDF–17M

Select item 103600432.

Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic

Justine A. Gelzinis, Melanie K. Szahaj, Roelof H. Bekendam, Sienna E. Wurl, Megan M. Pantos, Christina A. Verbetsky, Alexandre Dufresne, Meghan Shea, Kaitlind C. Howard, Oleg V. Tsodikov, Sylvie Garneau-Tsodikova, Jeffrey I. Zwicker, Daniel R. Kennedy

FASEB J. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: FASEB J. 2023 May; 37(5): e22914. doi: 10.1096/fj.202201952R

Correction in:: FASEB J. 2024 Jan; 38(1): e23393.

PMCID:: PMC10360043

Article PDF–1.5M

Select item 88100693.

Zafirlukast ameliorates Docetaxel-induced activation of NOD-like receptor protein 3 (NLRP3) inflammasome, mediated by sirtuin1 (SIRT1) in hepatocytes

Ziyi Guo, Xunjin Zeng, Yu Zheng

Bioengineered. 2021; 12(2): 11030–11040. Published online 2021 Nov 30. doi: 10.1080/21655979.2021.2005895

PMCID:: PMC8810069

Article PDF–1.1M

Select item 89991274.

Zafirlukast Induces VHL- and HIF-2α-Dependent Oxidative Cell Death in 786-O Clear Cell Renal Carcinoma Cells

Christopher Wolf, Sonja Smith, Sjoerd J. L. van Wijk

Int J Mol Sci. 2022 Apr; 23(7): 3567. Published online 2022 Mar 25. doi: 10.3390/ijms23073567

PMCID:: PMC8999127

Article PDF–3.0M

Select item 68806305.

Zafirlukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces the Effect of Advanced Glycation End-Products in Rat Renal Mesangial Cells In Vitro

Liping Yan, Ani Sun, Xinwei Xu

Med Sci Monit. 2019; 25: 8753–8763. Published online 2019 Nov 20. doi: 10.12659/MSM.918187

PMCID:: PMC6880630

Article PDF–2.4M

Select item 88401766.

In Silico Drug Repurposing Approach: Investigation of Mycobacterium tuberculosis FadD32 Targeted by FDA-Approved Drugs

Nolwazi Thobeka Portia Ngidi, Kgothatso Eugene Machaba, Ndumiso Nhlakanipho Mhlongo

Molecules. 2022 Feb; 27(3): 668. Published online 2022 Jan 20. doi: 10.3390/molecules27030668

PMCID:: PMC8840176

Article PDF–5.4M

Select item 89314267.

Zafirlukast inhibits the growth of lung adenocarcinoma via inhibiting TMEM16A channel activity

Sai Shi, Biao Ma, Fude Sun, Chang Qu, Gen Li, Donghong Shi, Wenxin Liu, Hailin Zhang, Hailong An

J Biol Chem. 2022 Mar; 298(3): 101731. Published online 2022 Feb 15. doi: 10.1016/j.jbc.2022.101731

PMCID:: PMC8931426

Article PDF–4.9M

Select item 4085038.

Asthma drug zafirlukast (Accolate): serious hepatic events

Eric Wooltorton

CMAJ. 2004 May 25; 170(11): 1668. doi: 10.1503/cmaj.1040720

PMCID:: PMC408503

Article PDF–223K

Select item 891259.

Lack of Effect of Zafirlukast on the Pharmacokinetics of Azithromycin, Clarithromycin, and 14-Hydroxyclarithromycin in Healthy Volunteers

Kevin W. Garey, Charles A. Peloquin, Paul G. Godo, Anne N. Nafziger, Guy W. Amsden

Antimicrob Agents Chemother. 1999 May; 43(5): 1152–1155. doi: 10.1128/aac.43.5.1152

PMCID:: PMC89125

Article PDF–63K

Select item 242666710.

Tolerance and rebound with zafirlukast in patients with persistent asthma

David W Reid, Neil L Misso, Shashi Aggarwal, Philip J Thompson, David P Johns, E Haydn Walters

J Negat Results Biomed. 2008; 7: 3. Published online 2008 May 19. doi: 10.1186/1477-5751-7-3

PMCID:: PMC2426667

Article PDF–318K

Select item 363293611.

Zafirlukast Inhibits Complexation of Lsr2 with DNA and Growth of Mycobacterium tuberculosis

Lucile Pinault, Jeong-Sun Han, Choong-Min Kang, Jimmy Franco, Donald R. Ronning

Antimicrob Agents Chemother. 2013 May; 57(5): 2134–2140. doi: 10.1128/AAC.02407-12

PMCID:: PMC3632936

Article PDF–765K

Select item 685099012.

CysLT1 receptor antagonists pranlukast and zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor

Eric E. Figueroa, Meghan Kramer, Kevin Strange, Jerod S. Denton

Am J Physiol Cell Physiol. 2019 Oct 1; 317(4): C857–C866. Published online 2019 Aug 7. doi: 10.1152/ajpcell.00281.2019

PMCID:: PMC6850990

Article

Select item 967305213.

The efficacy of Zafirlukast as a SARS-CoV-2 helicase inhibitor in adult patients with moderate COVID-19 Pneumonia (pilot randomized clinical trial)

M.Al Ghobain, F. Rebh, A. Saad, A.H. Khan, N. Mehyar, A. Mashhour, I. Islam, Y. Alobaida, A.S. Alaskar, M. Boudjelal, M.Al Jeraisy

J Infect Public Health. 2022 Dec; 15(12): 1546–1550. Published online 2022 Nov 17. doi: 10.1016/j.jiph.2022.11.016

PMCID:: PMC9673052

Article PDF–567K

Select item 174577414.

Effect of leukotriene receptor antagonist therapy on the risk of asthma exacerbations in patients with mild to moderate asthma: an integrated analysis of zafirlukast trials

N. Barnes, C. Miller

Thorax. 2000 Jun; 55(6): 478–483. doi: 10.1136/thorax.55.6.478

PMCID:: PMC1745774

Summary PDF–161K

Select item 174483215.

Zafirlukast for severe recurrent vulvovaginal candidiasis: an open label pilot study

D White, A Vanthuyne, P Wood, J Ayres

Sex Transm Infect. 2004 Jun; 80(3): 219–222. doi: 10.1136/sti.2002.003491

PMCID:: PMC1744832

Summary PDF–60K

Select item 282619916.

Concentration dependent non-CysLT₁ receptor mediated inhibitory activity of leukotriene receptor antagonists

Grzegorz Woszczek, Li-Yuan Chen, Sara Alsaaty, Sahrudaya Nagineni, James H. Shelhamer

J Immunol. Author manuscript; available in PMC 2011 Feb 15.

Published in final edited form as: J Immunol. 2010 Feb 15; 184(4): 2219–2225. Published online 2010 Jan 18. doi: 10.4049/jimmunol.0900071

PMCID:: PMC2826199

Article PDF–975K

Select item 214481117.

Leukotriene-receptor antagonists. Role in asthma management.

A. D. D'Urzo, K. R. Chapman

Can Fam Physician. 2000 Apr; 46: 872–879.

PMCID:: PMC2144811

Summary Page Browse PDF–63K

Select item 589989018.

An innovative high-throughput screening approach for discovery of small molecules that inhibit TNF Receptors

Chih Hung Lo, Nagamani Vunnam, Andrew K. Lewis, Ting-Lan Chiu, Benjamin E. Brummel, Tory M. Schaaf, Benjamin D. Grant, Prachi Bawaskar, David D. Thomas, Jonathan N. Sachs

SLAS Discov. Author manuscript; available in PMC 2018 Apr 15.

Published in final edited form as: SLAS Discov. 2017 Sep; 22(8): 950–961. Published online 2017 May 22. doi: 10.1177/2472555217706478